Evolution Labs Oro-Mucosal-Sublingual
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D9GI Oro-Mucosal Background Paper
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Easy To Take
One of the main benefits of a tincture is that it is very easy to take. Drops of tincture solution are squeezed out through an eyedropper syringe under your tongue. There the solution is left to be absorbed (not swallowed) into your bloodstream through a process called osmosis. Osmosis occurs when molecules of a solvent (the ethanol and all the cannabis chemical it contains) pass through a semipermeable membrane (the tissue under your tongue) from a less concentrated solution into a more concentrated one on the other side in order to equalize the concentrations on both sides of the membrane.
Source: http://www.silver-health.co.uk/absorb-colloidal-silver/?doing_wp_cron=1449193306.5657439231872558593750
The major advantage of this sublingual administration method is that the medicine is rapidly absorbed through the the sublingual artery, your body’s main blood supply to the tongue. This artery arises from the external carotid artery, which, in turn, is close to the internal carotid artery which allows the medicine to quickly reach the brain. Additionally, the tincture doesn’t come in contact with the acids in your stomach like other edibles do. That fact alone serves to keep many of the beneficial chemicals in your cannabis tincture more complete and more readily available for use in your body. Sublingual absorption effectively removes a step—digestion—that can have slight but destructive consequences to the chemical makeup of the cannabis you put in your body.
This process of osmosis through the sublingual artery is ideal for patients suffering from pain due to gastrointestinal difficulties such as ulcers, hyperactive gut, coeliac disease and other digestion issues that might make an edible less palatable.
Cannabis smoke is in no way conclusively linked to any kind of cancer, however sublingual ingestion of cannabis tinctures is, of course, ideal for anyone who may be concerned about the perceived health risks of inhaling smoke of any kind into one’s lungs.
Tinctures are also ideal for anyone who may be too sick, too old, or too young (like Charlotte Figi was) to properly smoke or even vaporize cannabis. Tinctures allow people of all ages to realize the beneficial health effects that the cannabis plant has to offer.
Tinctures are also well regarded by seasoned stoners as an effective recreational high that you can stealthily enjoy in most social situations without drawing the same attention to yourself that you would if you lit a massive blunt in the middle of a crowd. It’s a proven fact that the smell of cannabis smoke can, and often will, draw a lot of attention. And depending on where you are, that could be a good thing or a bad thing. Tinctures draw none of this attention. All it takes is 2 to 3 drops under the tongue—a process that takes less than 20 seconds—to achieve much the same high as smoking a joint. No muss. No fuss. No tell-tale smell. Just the psychoactive high or the medicinal benefits you crave.
Source: http://bangordailynews.com/2012/09/17/health/medical-pot-treats-boys-epilepsy-without-getting-him-high/
The onset of the euphoric effects of a tincture will kick in just a little bit slower than they would if you were smoking but much faster than they would from an edible of the same strain of weed. You’ll feel the effects of 2 to 3 drops under your tongue within about 15 minutes. This is why tinctures are infinitely superior to edibles in terms of the process of trial and error by which you determine the right amount of cannabis that your unique endocannabinoid system requires in order to feel optimal. The more scientific name for this “try-and-see” practice is titration. You’ll often hear this term bandied around by those in the know because it’s easier to say than, “the process of trial and error by which you determine the right amount of cannabis that your unique endocannabinoid system requires in order to feel optimal.” See what we mean? Why say 26 words when you can say just one and mean the same thing? Start using the word titration now so you at least sound like you know what you’re talking about.
Source: https://www.youtube.com/watch?v=_MnWaDe0pFQ
When administering these drops of canna-goodness, it’s important to remember NOT to swallow your tincture if you want the full benefits of sublingual absorption. You can, of course, swallow your tincture, or even add it to tea, juice or food like many patients do. Nothing bad will happen. However, the delta-9-THC in your tincture will transform into 11-Hydroxy-THC when it passes through the liver of your gastrointestinal tract. And depending on your metabolism, this can take up to two hours or more to occur. That means that you’ll have to wait at least two hours to feel the effects. On top of that, they might be slightly different because of the presence of 11-Hydroxy-THC.
According to The National Organization for the Reform of Marijuana Laws (NORML), ingested 11-Hydroxy-THC can be felt up to 4 to 5 times stronger than inhaled Delta-9-THC. But, according to Jay R. Cavanaugh, Ph.D., it can take 4 to 10 times as much oral cannabis in order to feel the same effects.
Source: https://patients4medicalmarijuana.wordpress.com/2011/01/13/pregnancy-and-medical-marijuana-can-pot-help-pregnant-women-with-vomiting-and-nausea/
So again, remember not to swallow or the tincture will most likely take much longer to be effective. Just let the tincture solution dissolve under your tongue for about 30 seconds.
It’s also important to remember that you are also consuming alcohol—albeit a tiny amount—when you administer a tincture. In addition to that alcohol, your tincture will likely contain about 60% THC. That’s a lot! The combination of the alcohol and the THC can pack a hefty punch so start slow with your tincture titration. Get a feel for the potency of your medication and then gradually increase you dosage. We suggest starting with 2 or 3 drops at a time. Err on the side of caution and start with 2 drops (or less) if you’re new to cannabis consumption. After you administer your drops, wait at least an hour and a half before consuming more. This gives the chemicals in the tincture time to spread throughout your body and gives your body time to fully process the cannabinoids. After an hour and half, you should know for sure how the amount of tincture you took will impact your body and mind. Until you gain some experience with tincture titration, we recommend that you wait another hour and a half before you try another does. This will give your body time to flush the system so you’re not stacking new THC (or CBD) on top of old THC.
Quoted from:https://honestmarijuana.com/marijuana-tinctures/?age-verified=0315cecfdc